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Mild and repetitive very mild axonal stretch injury triggers cystoskeletal mislocalization and growth cone collapse

Diffuse axonal injury is a hallmark pathological consequence of non-penetrative traumatic brain injury (TBI) and yet the axonal responses to stretch injury are not fully understood at the cellular level. Here, we investigated the effects of mild (5%), very mild (0.5%) and repetitive very mild (2×0.5...

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Detalles Bibliográficos
Autores principales: Yap, Yiing C., King, Anna E., Guijt, Rosanne M., Jiang, Tongcui, Blizzard, Catherine A., Breadmore, Michael C., Dickson, Tracey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417565/
https://www.ncbi.nlm.nih.gov/pubmed/28472086
http://dx.doi.org/10.1371/journal.pone.0176997