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Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing

Until recently, vitamin K antagonists (VKAs) were the mainstay of oral anticoagulant treatment with bleeding as the most prevalent adverse effect. One to four percent of patients experience major bleeding episodes, while clinically relevant bleeding occurs in up to 20%. At this moment no laboratory...

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Detalles Bibliográficos
Autores principales: Bloemen, Saartje, Zwaveling, Suzanne, ten Cate, Hugo, ten Cate-Hoek, Arina, de Laat, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417600/
https://www.ncbi.nlm.nih.gov/pubmed/28472104
http://dx.doi.org/10.1371/journal.pone.0176967