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Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade glioma

Pediatric high-grade gliomas represent 8–12% of all primary tumors of the nervous system in children. Five-year survival for these pediatric aggressive tumors is poor (15–35%) indicating the need to develop better treatments for pediatric high-grade gliomas. In this work we used SF188 and SJ-GBM2 ce...

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Detalles Bibliográficos
Autores principales: Sanchez-Diaz, Patricia C., Chang, Judy C., Moses, Emily S., Dao, Tu, Chen, Yidong, Hung, Jaclyn Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417601/
https://www.ncbi.nlm.nih.gov/pubmed/28472177
http://dx.doi.org/10.1371/journal.pone.0176879