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STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes

The JAK/STAT signaling pathway is suggested to play an important role in the pathogenesis of psoriasis, and recently JAK/STAT inhibitors have shown promising results in psoriasis treatment. The present study aimed to characterize the role of STAT2 in psoriasis. We demonstrated an increased expressio...

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Detalles Bibliográficos
Autores principales: Johansen, Claus, Rittig, Anne Hald, Mose, Maike, Bertelsen, Trine, Weimar, Isabella, Nielsen, Jakob, Andersen, Thomas, Rasmussen, Tue Kruse, Deleuran, Bent, Iversen, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417613/
https://www.ncbi.nlm.nih.gov/pubmed/28472186
http://dx.doi.org/10.1371/journal.pone.0176994