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Emergence of CXCR4-tropic HIV-1 variants followed by rapid disease progression in hemophiliac slow progressors

OBJECTIVE: The association between emergence of CXCR4-tropic HIV-1 variants (X4 variants) and disease progression of HIV-1 infection has been reported. However, it is not known whether the emergence of X4 variants is the cause or result of HIV-1 disease progression. We tried to answer this question....

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Detalles Bibliográficos
Autores principales: Hayashida, Tsunefusa, Tsuchiya, Kiyoto, Kikuchi, Yoshimi, Oka, Shinichi, Gatanaga, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417636/
https://www.ncbi.nlm.nih.gov/pubmed/28472121
http://dx.doi.org/10.1371/journal.pone.0177033