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Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae

In Saccharomyces cerevisiae mitochondrial dysfunction induces retrograde signaling, a pathway of communication from mitochondria to the nucleus that promotes a metabolic remodeling to ensure sufficient biosynthetic precursors for replication. Rtg2p is a positive modulator of this pathway that is als...

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Detalles Bibliográficos
Autores principales: Rios-Anjos, Rafaela Maria, Camandona, Vittoria de Lima, Bleicher, Lucas, Ferreira-Junior, Jose Ribamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417653/
https://www.ncbi.nlm.nih.gov/pubmed/28472157
http://dx.doi.org/10.1371/journal.pone.0177090