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Induction of mitophagy-mediated antitumor activity with folate-appended methyl-β-cyclodextrin

Mitophagy is the specific autophagic elimination system of mitochondria, which regulates cellular survival via the removal of damaged mitochondria. Recently, we revealed that folate-appended methyl-β-cyclodextrin (FA-M-β-CyD) provides selective antitumor activity in folate receptor-α (FR-α)-expressi...

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Detalles Bibliográficos
Autores principales: Kameyama, Kazuhisa, Motoyama, Keiichi, Tanaka, Nao, Yamashita, Yuki, Higashi, Taishi, Arima, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417668/
https://www.ncbi.nlm.nih.gov/pubmed/28496320
http://dx.doi.org/10.2147/IJN.S133482