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Induction of mitophagy-mediated antitumor activity with folate-appended methyl-β-cyclodextrin
Mitophagy is the specific autophagic elimination system of mitochondria, which regulates cellular survival via the removal of damaged mitochondria. Recently, we revealed that folate-appended methyl-β-cyclodextrin (FA-M-β-CyD) provides selective antitumor activity in folate receptor-α (FR-α)-expressi...
Autores principales: | Kameyama, Kazuhisa, Motoyama, Keiichi, Tanaka, Nao, Yamashita, Yuki, Higashi, Taishi, Arima, Hidetoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417668/ https://www.ncbi.nlm.nih.gov/pubmed/28496320 http://dx.doi.org/10.2147/IJN.S133482 |
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