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Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion
TAR DNA binding protein (TDP-43) is a 43 kD, predominately nuclear, protein involved in RNA metabolism. Of clinical significance is that the majority of amyotrophic lateral sclerosis (ALS) patients display abnormal accumulation of misfolded TDP-43 in the cytoplasm, which is coincident with a loss of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417676/ https://www.ncbi.nlm.nih.gov/pubmed/28472174 http://dx.doi.org/10.1371/journal.pone.0177005 |