Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion

TAR DNA binding protein (TDP-43) is a 43 kD, predominately nuclear, protein involved in RNA metabolism. Of clinical significance is that the majority of amyotrophic lateral sclerosis (ALS) patients display abnormal accumulation of misfolded TDP-43 in the cytoplasm, which is coincident with a loss of...

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Detalles Bibliográficos
Autores principales: Dzieciolowska, Stefania, Drapeau, Pierre, Armstrong, Gary Alan Barclay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417676/
https://www.ncbi.nlm.nih.gov/pubmed/28472174
http://dx.doi.org/10.1371/journal.pone.0177005

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