Cargando…

Sendai Virus Mucosal Vaccination Establishes Lung-Resident Memory CD8 T Cell Immunity and Boosts BCG-Primed Protection against TB in Mice

Accumulating evidence has shown the protective role of CD8(+) T cells in vaccine-induced immunity against Mycobacterium tuberculosis (Mtb) despite controversy over their role in natural immunity. However, the current vaccine BCG is unable to induce sufficient CD8(+) T cell responses, especially in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Zhidong, Wong, Ka-Wing, Zhao, Hui-Min, Wen, Han-Li, Ji, Ping, Ma, Hui, Wu, Kang, Lu, Shui-Hua, Li, Feng, Li, Zhong-Ming, Shu, Tsugumine, Xu, Jian-Qing, Lowrie, Douglas B., Fan, Xiao-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417795/
https://www.ncbi.nlm.nih.gov/pubmed/28342639
http://dx.doi.org/10.1016/j.ymthe.2017.02.018