Inhibition of the BET family of epigenetic reader proteins: A novel principle for modulating gene expression in IgE‐activated mast cells

INTRODUCTION: The BET family of bromodomain‐containing proteins constitute epigenetic readers that bind to acetylated lysine residues of core histones, thereby translating epigenetic histone marks to effects on gene expression. BET inhibitors are currently emerging as promising therapeutic agents fo...

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Detalles Bibliográficos
Autores principales: Garcia‐Faroldi, Gianni, Rönnberg, Elin, Grujic, Mirjana, Pejler, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418135/
https://www.ncbi.nlm.nih.gov/pubmed/28474499
http://dx.doi.org/10.1002/iid3.150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418135/
https://www.ncbi.nlm.nih.gov/pubmed/28474499
http://dx.doi.org/10.1002/iid3.150

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