Pharmacological analysis of the increases in heart rate and diastolic blood pressure produced by (S)-isometheptene and (R)-isometheptene in pithed rats

BACKGROUND: Isometheptene is a sympathomimetic drug effective in acute migraine treatment. It is composed of two enantiomers with diverse pharmacological properties. This study investigated in pithed rats the cardiovascular effects of (S)- isometheptene and (R)-isometheptene, and the pharmacological...

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Detalles Bibliográficos
Autores principales: Labastida-Ramírez, Alejandro, Rubio-Beltrán, Eloísa, Hernández-Abreu, Oswaldo, Daugherty, Bruce L., MaassenVanDenBrink, Antoinette, Villalón, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418177/
https://www.ncbi.nlm.nih.gov/pubmed/28474252
http://dx.doi.org/10.1186/s10194-017-0761-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418177/
https://www.ncbi.nlm.nih.gov/pubmed/28474252
http://dx.doi.org/10.1186/s10194-017-0761-y

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