Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion

Age‐related declines in skeletal muscle regeneration have been attributed to muscle stem cell (MuSC) dysfunction. Aged MuSCs display a fibrogenic conversion, leading to fibrosis and impaired recovery after injury. Although studies have demonstrated the influence of in vitro substrate characteristics...

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Detalles Bibliográficos
Autores principales: Stearns‐Reider, Kristen M., D'Amore, Antonio, Beezhold, Kevin, Rothrauff, Benjamin, Cavalli, Loredana, Wagner, William R., Vorp, David A., Tsamis, Alkiviadis, Shinde, Sunita, Zhang, Changqing, Barchowsky, Aaron, Rando, Thomas A., Tuan, Rocky S., Ambrosio, Fabrisia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418187/
https://www.ncbi.nlm.nih.gov/pubmed/28371268
http://dx.doi.org/10.1111/acel.12578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418187/
https://www.ncbi.nlm.nih.gov/pubmed/28371268
http://dx.doi.org/10.1111/acel.12578

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