Age‐related decline in BubR1 impairs adult hippocampal neurogenesis

Aging causes significant declines in adult hippocampal neurogenesis and leads to cognitive disability. Emerging evidence demonstrates that decline in the mitotic checkpoint kinase BubR1 level occurs with natural aging and induces progeroid features in both mice and children with mosaic variegated an...

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Detalles Bibliográficos
Autores principales: Yang, Zhongxi, Jun, Heechul, Choi, Chan‐II, Yoo, Ki Hyun, Cho, Chang Hoon, Hussaini, Syed Mohammed Qasim, Simmons, Ambrosia J., Kim, Seonhee, van Deursen, Jan M., Baker, Darren J., Jang, Mi‐Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418205/
https://www.ncbi.nlm.nih.gov/pubmed/28383136
http://dx.doi.org/10.1111/acel.12594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418205/
https://www.ncbi.nlm.nih.gov/pubmed/28383136
http://dx.doi.org/10.1111/acel.12594

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