The Electrogenic Na(+)/K(+) Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study

Background: Cellular repolarization abnormalities occur unpredictably due to disease and drug effects, and can occur even in cardiomyocytes that exhibit normal action potentials (AP) under control conditions. Variability in ion channel densities may explain differences in this susceptibility to repo...

Descripción completa

Detalles Bibliográficos
Autores principales: Britton, Oliver J., Bueno-Orovio, Alfonso, Virág, László, Varró, András, Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418229/
https://www.ncbi.nlm.nih.gov/pubmed/28529489
http://dx.doi.org/10.3389/fphys.2017.00278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418229/
https://www.ncbi.nlm.nih.gov/pubmed/28529489
http://dx.doi.org/10.3389/fphys.2017.00278

Ejemplares similares