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The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection

Mycobacterium bovis (M. bovis) is the pathogen of animals and humans that can replicate in the phagosomes of myeloid cells. Cytosolic detection of bacterial products plays a crucial role in initiating the innate immune response, including autophagy activation and interferon-β (IFN-β) release. Althou...

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Detalles Bibliográficos
Autores principales: Chunfa, Liu, Xin, Sun, Qiang, Li, Sreevatsan, Srinand, Yang, Lifeng, Zhao, Deming, Zhou, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418236/
https://www.ncbi.nlm.nih.gov/pubmed/28529930
http://dx.doi.org/10.3389/fcimb.2017.00169