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Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells

Neferine, a bisbenzylisoquinoline alkaloid isolated from the green seed embryos of Lotus (Nelumbo nucifera Gaertn), has been previously shown to have various anti-cancer effects. In the present study, we evaluated the effect of neferine in terms of P-glycoprotein (P-gp) inhibition via in vitro cytot...

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Detalles Bibliográficos
Autores principales: Kadioglu, Onat, Law, Betty Y. K., Mok, Simon W. F., Xu, Su-Wei, Efferth, Thomas, Wong, Vincent K. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418350/
https://www.ncbi.nlm.nih.gov/pubmed/28529482
http://dx.doi.org/10.3389/fphar.2017.00238