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CD21(int) CD23(+) follicular B cells express antigen‐specific secretory IgM mRNA as primary and memory responses

CD21(int) CD23(+) IgM(+) mouse follicular B cells comprise the bulk of the mature B‐cell compartment, but it is not known whether these cells contribute to the humoral antibody response. We show using a direct RT‐PCR method for antigen‐specific VH, that FACS‐sorted mouse CD21(int) CD23(+) B cells ex...

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Detalles Bibliográficos
Autores principales: Meng, Qing‐Hai, White, Harry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418461/
https://www.ncbi.nlm.nih.gov/pubmed/28190261
http://dx.doi.org/10.1111/imm.12724