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Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme

Since their initial characterization over 30 years ago, it has been believed that the archaeal B-family DNA polymerases are single-subunit enzymes. This contrasts with the multi-subunit B-family replicative polymerases of eukaryotes. Here we reveal that the highly studied PolB1 from Sulfolobus solfa...

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Detalles Bibliográficos
Autores principales: Yan, Jiangyu, Beattie, Thomas R., Rojas, Adriana L., Schermerhorn, Kelly, Gristwood, Tamzin, Trinidad, Jonathan C., Albers, Sonja V., Roversi, Pietro, Gardner, Andrew F., Abrescia, Nicola G. A., Bell, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418573/
https://www.ncbi.nlm.nih.gov/pubmed/28462924
http://dx.doi.org/10.1038/ncomms15075