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Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancer

BACKGROUND: Estrogenic signals are suggested to have protection roles in the development of colorectal cancer (CRC). The G protein-coupled estrogen receptor (GPER) has been reported to mediate non-genomic effects of estrogen in hormone related cancers except CRC. Its expression and functions in CRC...

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Detalles Bibliográficos
Autores principales: Liu, Qiao, Chen, Zhuojia, Jiang, Guanmin, Zhou, Yan, Yang, Xiangling, Huang, Hongbin, Liu, Huanliang, Du, Jun, Wang, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418684/
https://www.ncbi.nlm.nih.gov/pubmed/28476123
http://dx.doi.org/10.1186/s12943-017-0654-3