A critical examination of the recently reported crystal structures of the human SMN protein

A recent publication by Seng et al. in this journal reports the crystallographic structure of refolded, full-length SMN protein and two disease-relevant derivatives thereof. Here, we would like to suggest that at least two of the structures reported in that study are incorrect. We present evidence t...

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Detalles Bibliográficos
Autores principales: Weiss, Manfred S., Diederichs, Kay, Read, Randy J., Panjikar, Santosh, Van Duyne, Gregory D., Matera, A. Gregory, Fischer, Utz, Grimm, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418738/
https://www.ncbi.nlm.nih.gov/pubmed/27577872
http://dx.doi.org/10.1093/hmg/ddw298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418738/
https://www.ncbi.nlm.nih.gov/pubmed/27577872
http://dx.doi.org/10.1093/hmg/ddw298

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