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A critical examination of the recently reported crystal structures of the human SMN protein
A recent publication by Seng et al. in this journal reports the crystallographic structure of refolded, full-length SMN protein and two disease-relevant derivatives thereof. Here, we would like to suggest that at least two of the structures reported in that study are incorrect. We present evidence t...
Autores principales: | Weiss, Manfred S., Diederichs, Kay, Read, Randy J., Panjikar, Santosh, Van Duyne, Gregory D., Matera, A. Gregory, Fischer, Utz, Grimm, Clemens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418738/ https://www.ncbi.nlm.nih.gov/pubmed/27577872 http://dx.doi.org/10.1093/hmg/ddw298 |
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