Cargando…

Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts

Substantial variability exists in the presentation of complex neurological disorders, and the study of single nucleotide polymorphisms (SNPs) has shed light on disease mechanisms and pathophysiological variability in some cases. However, the vast majority of disease-linked SNPs have unidentified pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramachandran, Shyam, Coffin, Stephanie L., Tang, Tin-Yun, Jobaliya, Chintan D., Spengler, Ryan M., Davidson, Beverly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418741/
https://www.ncbi.nlm.nih.gov/pubmed/28171541
http://dx.doi.org/10.1093/hmg/ddw317