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Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity

BACKGROUND: As the primary immune response cell in the central nervous system, microglia constantly monitor the microenvironment and respond rapidly to stress, infection, and injury, making them important modulators of neuroinflammatory responses. In diseases such as Parkinson’s disease, Alzheimer’s...

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Detalles Bibliográficos
Autores principales: Kirkley, Kelly S., Popichak, Katriana A., Afzali, Maryam F., Legare, Marie E., Tjalkens, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418760/
https://www.ncbi.nlm.nih.gov/pubmed/28476157
http://dx.doi.org/10.1186/s12974-017-0871-0