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Rhinovirus C targets ciliated airway epithelial cells

BACKGROUND: The Rhinovirus C (RV-C), first identified in 2006, produce high symptom burdens in children and asthmatics, however, their primary target host cell in the airways remains unknown. Our primary hypotheses were that RV-C target ciliated airway epithelial cells (AECs), and that cell specific...

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Detalles Bibliográficos
Autores principales: Griggs, Theodor F., Bochkov, Yury A., Basnet, Sarmila, Pasic, Thomas R., Brockman-Schneider, Rebecca A., Palmenberg, Ann C., Gern, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418766/
https://www.ncbi.nlm.nih.gov/pubmed/28472984
http://dx.doi.org/10.1186/s12931-017-0567-0