Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line

BACKGROUND: There is compelling evidence associating senescent cells with the malignant progression of tumours. Of all senescence-related mechanisms, the so-called senescence-associated secretory phenotype (SASP) has attracted much attention. Since the pro-inflammatory cytokines IL-6 and IL-8 are co...

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Detalles Bibliográficos
Autores principales: Ortiz-Montero, Paola, Londoño-Vallejo, Arturo, Vernot, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418812/
https://www.ncbi.nlm.nih.gov/pubmed/28472950
http://dx.doi.org/10.1186/s12964-017-0172-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418812/
https://www.ncbi.nlm.nih.gov/pubmed/28472950
http://dx.doi.org/10.1186/s12964-017-0172-3

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