Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes

During spermatogenesis, germ cells that fail to synapse their chromosomes or fail to undergo meiotic sex chromosome inactivation (MSCI) are eliminated via apoptosis during mid-pachytene. Previous work showed that Y-linked genes Zfy1 and Zfy2 act as ‘executioners’ for this checkpoint, and that wrongf...

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Detalles Bibliográficos
Autores principales: Vernet, Nadège, Mahadevaiah, Shantha K., de Rooij, Dirk G., Burgoyne, Paul S., Ellis, Peter J. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418838/
https://www.ncbi.nlm.nih.gov/pubmed/27742779
http://dx.doi.org/10.1093/hmg/ddw344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418838/
https://www.ncbi.nlm.nih.gov/pubmed/27742779
http://dx.doi.org/10.1093/hmg/ddw344

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