A Flexible Workflow for Automated Bioluminescent Kinase Selectivity Profiling

Kinase profiling during drug discovery is a necessary process to confirm inhibitor selectivity and assess off-target activities. However, cost and logistical limitations prevent profiling activities from being performed in-house. We describe the development of an automated and flexible kinase profil...

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Detalles Bibliográficos
Autores principales: Worzella, Tracy, Butzler, Matt, Hennek, Jacquelyn, Hanson, Seth, Simdon, Laura, Goueli, Said, Cowan, Cris, Zegzouti, Hicham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418932/
https://www.ncbi.nlm.nih.gov/pubmed/28095176
http://dx.doi.org/10.1177/2211068216677248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418932/
https://www.ncbi.nlm.nih.gov/pubmed/28095176
http://dx.doi.org/10.1177/2211068216677248

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