Cargando…

Computational identification of mutually homologous Zika virus miRNAs that target microcephaly genes

Background Zika virus (ZIKV) has been associated with a variety of neuropathologies, including microcephaly. We hypothesize that ZIKV genes activate host microRNAs (miRNAs) causing dysfunctional development of human fetal brains. Objectives/methods A bioinformatics search for miRNA genome-wide bindi...

Descripción completa

Detalles Bibliográficos
Autores principales: McLean, Ewen, Bhattarai, Roshan, Hughes, Brandon W., Mahalingam, Kuhanandha, Bagasra, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418939/
https://www.ncbi.nlm.nih.gov/pubmed/28385119
http://dx.doi.org/10.1080/19932820.2017.1304505