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Computational identification of mutually homologous Zika virus miRNAs that target microcephaly genes
Background Zika virus (ZIKV) has been associated with a variety of neuropathologies, including microcephaly. We hypothesize that ZIKV genes activate host microRNAs (miRNAs) causing dysfunctional development of human fetal brains. Objectives/methods A bioinformatics search for miRNA genome-wide bindi...
Autores principales: | McLean, Ewen, Bhattarai, Roshan, Hughes, Brandon W., Mahalingam, Kuhanandha, Bagasra, Omar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418939/ https://www.ncbi.nlm.nih.gov/pubmed/28385119 http://dx.doi.org/10.1080/19932820.2017.1304505 |
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