Analytical ultracentrifugation with fluorescence detection system reveals differences in complex formation between recombinant human TNF and different biological TNF antagonists in various environments

A number of studies have attempted to elucidate the binding mechanism between tumor necrosis factor (TNF) and clinically relevant antagonists. None of these studies, however, have been conducted as close as possible to physiologic conditions, and so the relationship between the size distribution of...

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Detalles Bibliográficos
Autores principales: Krayukhina, Elena, Noda, Masanori, Ishii, Kentaro, Maruno, Takahiro, Wakabayashi, Hirotsugu, Tada, Minoru, Suzuki, Takuo, Ishii-Watabe, Akiko, Kato, Masahiko, Uchiyama, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419078/
https://www.ncbi.nlm.nih.gov/pubmed/28387583
http://dx.doi.org/10.1080/19420862.2017.1297909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419078/
https://www.ncbi.nlm.nih.gov/pubmed/28387583
http://dx.doi.org/10.1080/19420862.2017.1297909

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