Resolving the micro-heterogeneity and structural integrity of monoclonal antibodies by hybrid mass spectrometric approaches

For therapeutic monoclonal antibodies (mAbs), detailed analysis of the structural integrity and heterogeneity, which results from multiple types of post-translational modifications (PTMs), is relevant to various processes, including product characterization, storage stability and quality control. De...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Wang, Guanbo, Song, Ting, Lebrilla, Carlito B., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419080/
https://www.ncbi.nlm.nih.gov/pubmed/28281873
http://dx.doi.org/10.1080/19420862.2017.1290033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419080/
https://www.ncbi.nlm.nih.gov/pubmed/28281873
http://dx.doi.org/10.1080/19420862.2017.1290033

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