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Rodent heart failure models do not reflect the human circulating microRNA signature in heart failure

INTRODUCTION: We recently identified a set of plasma microRNAs (miRNAs) that are downregulated in patients with heart failure in comparison with control subjects. To better understand their meaning and function, we sought to validate these circulating miRNAs in 3 different well-established rat and m...

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Detalles Bibliográficos
Autores principales: Vegter, Eline L., Ovchinnikova, Ekaterina S., Silljé, Herman H. W., Meems, Laura M. G., van der Pol, Atze, van der Velde, A. Rogier, Berezikov, Eugene, Voors, Adriaan A., de Boer, Rudolf A., van der Meer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419653/
https://www.ncbi.nlm.nih.gov/pubmed/28475616
http://dx.doi.org/10.1371/journal.pone.0177242