Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q

Trinucleotide repeat (TNR) instability is associated with human neurodegenerative diseases and cancer. Recent studies have pointed out that DNA base excision repair (BER) mediated by DNA polymerase β (pol β) plays a crucial role in governing somatic TNR instability in a damage-location dependent man...

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Detalles Bibliográficos
Autores principales: Ren, Yaou, Lai, Yanhao, Laverde, Eduardo E., Lei, Ruipeng, Rein, Hayley L., Liu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419657/
https://www.ncbi.nlm.nih.gov/pubmed/28475635
http://dx.doi.org/10.1371/journal.pone.0177299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419657/
https://www.ncbi.nlm.nih.gov/pubmed/28475635
http://dx.doi.org/10.1371/journal.pone.0177299

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