Cargando…
Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q
Trinucleotide repeat (TNR) instability is associated with human neurodegenerative diseases and cancer. Recent studies have pointed out that DNA base excision repair (BER) mediated by DNA polymerase β (pol β) plays a crucial role in governing somatic TNR instability in a damage-location dependent man...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419657/ https://www.ncbi.nlm.nih.gov/pubmed/28475635 http://dx.doi.org/10.1371/journal.pone.0177299 |