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When more is less: Emergent suppressive interactions in three-drug combinations

BACKGROUND: In drug-drug interactions, there are surprising cases in which the growth inhibition of bacteria by a single antibiotic decreases when a second antibiotic is added. These interactions are termed suppressive and have been argued to have the potential to limit the evolution of resistance....

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Detalles Bibliográficos
Autores principales: Beppler, Casey, Tekin, Elif, White, Cynthia, Mao, Zhiyuan, Miller, Jeffrey H., Damoiseaux, Robert, Savage, Van M., Yeh, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420147/
https://www.ncbi.nlm.nih.gov/pubmed/28477626
http://dx.doi.org/10.1186/s12866-017-1017-3