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Dioxins and related environmental contaminants increase TDP-43 levels

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative condition that is characterized by progressive loss of motor neurons and the accumulation of aggregated TAR DNA Binding Protein-43 (TDP-43, gene: TARDBP). Increasing evidence indicates that environmental factors cont...

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Detalles Bibliográficos
Autores principales:	Ash, Peter E. A., Stanford, Elizabeth A., Al Abdulatif, Ali, Ramirez-Cardenas, Alejandra, Ballance, Heather I., Boudeau, Samantha, Jeh, Amanda, Murithi, James M., Tripodis, Yorghos, Murphy, George J., Sherr, David H., Wolozin, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420162/ https://www.ncbi.nlm.nih.gov/pubmed/28476168 http://dx.doi.org/10.1186/s13024-017-0177-9

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