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Parameter identifiability analysis and visualization in large-scale kinetic models of biosystems
BACKGROUND: Kinetic models of biochemical systems usually consist of ordinary differential equations that have many unknown parameters. Some of these parameters are often practically unidentifiable, that is, their values cannot be uniquely determined from the available data. Possible causes are lack...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420165/ https://www.ncbi.nlm.nih.gov/pubmed/28476119 http://dx.doi.org/10.1186/s12918-017-0428-y |