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Intraflagellar Transport Dynein is Autoinhibited by Trapping of its Mechanical and Track-Binding Elements
Cilia are multi-functional organelles that are constructed using intraflagellar transport (IFT) of cargo to and from their tip. It is widely held that the retrograde IFT motor, dynein-2, must be controlled in order to reach the ciliary tip and then unleashed to power the return journey. However, the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420313/ https://www.ncbi.nlm.nih.gov/pubmed/28394326 http://dx.doi.org/10.1038/nsmb.3391 |