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High Sporozoite Antibody Titers in Conjunction with Microscopically Detectable Blood Infection Display Signatures of Protection from Clinical Malaria

Immunoepidemiological studies typically reveal slow, age-dependent acquisition of immune responses against Plasmodium falciparum sporozoites. Naturally acquired immunity against preerythrocytic stages is considered inadequate to confer protection against clinical malaria. To explore previously unrec...

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Detalles Bibliográficos
Autores principales: Offeddu, Vittoria, Olotu, Ally, Osier, Faith, Marsh, Kevin, Matuschewski, Kai, Thathy, Vandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421148/
https://www.ncbi.nlm.nih.gov/pubmed/28533773
http://dx.doi.org/10.3389/fimmu.2017.00488