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Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss

α-Synuclein is a protein involved in the pathogenesis of synucleinopathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). We investigated the role of neuronal α-Syn in myelin composition and abnormalities. The phospholipid content of purified...

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Detalles Bibliográficos
Autores principales: Grigoletto, Jessica, Pukaß, Katharina, Gamliel, Ayelet, Davidi, Dana, Katz-Brull, Rachel, Richter-Landsberg, Christiane, Sharon, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421332/
https://www.ncbi.nlm.nih.gov/pubmed/28482862
http://dx.doi.org/10.1186/s40478-017-0439-3