Early pathogenesis during infectious bursal disease in susceptible chickens is associated with changes in B cell genomic methylation and loss of genome integrity

We propose a model by which an increase in the genomic modification, 5-hydroxymethylcytosine (5hmC), contributes to B cell death within the chicken bursa of Fabricus (BF) infected with infectious bursal disease virus (IBDV). Our findings indicate that, following an IBDV infection, Rhode Island Red (...

Descripción completa

Detalles Bibliográficos
Autores principales: Ciccone, Nick A., Smith, Lorraine P., Mwangi, William, Boyd, Amy, Broadbent, Andrew J., Smith, Adrian L., Nair, Venugopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421744/
https://www.ncbi.nlm.nih.gov/pubmed/28322935
http://dx.doi.org/10.1016/j.dci.2017.03.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421744/
https://www.ncbi.nlm.nih.gov/pubmed/28322935
http://dx.doi.org/10.1016/j.dci.2017.03.014

Ejemplares similares