Lycorine Induces Apoptosis of A549 Cells via AMPK-Mammalian Target of Rapamycin (mTOR)-S6K Signaling Pathway

BACKGROUND: This study was designed to investigate the effect of lycorine (LY) on the AMPK-mTOR-S6K signaling pathway and to clarify its role in autophagy and apoptosis. MATERIAL/METHODS: Various concentrations of LY were used to treat non-small cell lung carcinoma A549 cells. The MTT assay was used...

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Detalles Bibliográficos
Autores principales: Zeng, Hui, Fu, Rong, Yan, Linxia, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421746/
https://www.ncbi.nlm.nih.gov/pubmed/28450693
http://dx.doi.org/10.12659/MSM.900742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421746/
https://www.ncbi.nlm.nih.gov/pubmed/28450693
http://dx.doi.org/10.12659/MSM.900742

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