Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models

Molecularly targeted therapeutics hold promise of revolutionizing treatments of advanced malignancies. However, a large number of patients do not respond to these treatments. Here, we take a systems biology approach to understand the molecular mechanisms that prevent breast cancer (BC) cells from re...

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Detalles Bibliográficos
Autores principales: Santra, Tapesh, Roche, Sandra, Conlon, Neil, O’Donovan, Norma, Crown, John, O’Connor, Robert, Kolch, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421758/
https://www.ncbi.nlm.nih.gov/pubmed/28481952
http://dx.doi.org/10.1371/journal.pone.0177058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421758/
https://www.ncbi.nlm.nih.gov/pubmed/28481952
http://dx.doi.org/10.1371/journal.pone.0177058

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