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TRPV2 knockout mice demonstrate an improved cardiac performance following myocardial infarction due to attenuated activity of peri-infarct macrophages

BACKGROUND: We have recently shown that the expression of the transient receptor potential vanilloid 2 channel, TRPV2, is upregulated in the peri-infarct zone 3–5 days following an acute myocardial infarction (AMI). Further analysis has demonstrated that invading monocytes maturing to macrophages me...

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Detalles Bibliográficos
Autores principales: Entin-Meer, Michal, Cohen, Lena, Hertzberg-Bigelman, Einat, Levy, Ran, Ben-Shoshan, Jeremy, Keren, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421795/
https://www.ncbi.nlm.nih.gov/pubmed/28481959
http://dx.doi.org/10.1371/journal.pone.0177132