Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo

Shp2 played an important role in cigarette-smoke-mediated inflammation, surfactant homeostasis and asthmatic airway remodeling. However, whether shp2 plays a key role in epithelium-associated allergic reaction is still unknown. In this study, LPS and OVA were observed to induce the production of IL-...

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Detalles Bibliográficos
Autores principales: Qiu, Zhangwei, Zhou, Jiesen, Liu, Fang, Qin, Xuejun, Dai, Yuanrong, Ke, Yuehai, Chen, Zhihua, Li, Wen, Ying, Songmin, Shen, Huahao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421800/
https://www.ncbi.nlm.nih.gov/pubmed/28481957
http://dx.doi.org/10.1371/journal.pone.0177334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421800/
https://www.ncbi.nlm.nih.gov/pubmed/28481957
http://dx.doi.org/10.1371/journal.pone.0177334

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