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A Sequence in the loop domain of hepatitis C virus E2 protein identified in silico as crucial for the selective binding to human CD81

Hepatitis C virus (HCV) is a species-specific pathogenic virus that infects only humans and chimpanzees. Previous studies have indicated that interactions between the HCV E2 protein and CD81 on host cells are required for HCV infection. To determine the crucial factors for species-specific interacti...

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Detalles Bibliográficos
Autores principales: Chang, Chun-Chun, Hsu, Hao-Jen, Yen, Jui-Hung, Lo, Shih-Yen, Liou, Je-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421814/
https://www.ncbi.nlm.nih.gov/pubmed/28481946
http://dx.doi.org/10.1371/journal.pone.0177383