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Azilsartan ameliorates apoptosis of dopaminergic neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinson’s disease

Loss of dopaminergic neurons within the substantia nigra (SN) is a pathological hallmark of Parkinsons disease (PD), which leads to the onset of motor symptoms. Previously, our in vitro studies revealed that Angiotensin II (Ang II) induced apoptosis of dopaminergic neurons through its type 1 recepto...

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Detalles Bibliográficos
Autores principales: Gao, Qing, Ou, Zhou, Jiang, Teng, Tian, You-Yong, Zhou, Jun-Shan, Wu, Liang, Shi, Jian-Quan, Zhang, Ying-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421830/
https://www.ncbi.nlm.nih.gov/pubmed/28445961
http://dx.doi.org/10.18632/oncotarget.15732