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Azilsartan ameliorates apoptosis of dopaminergic neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinson’s disease
Loss of dopaminergic neurons within the substantia nigra (SN) is a pathological hallmark of Parkinsons disease (PD), which leads to the onset of motor symptoms. Previously, our in vitro studies revealed that Angiotensin II (Ang II) induced apoptosis of dopaminergic neurons through its type 1 recepto...
Autores principales: | Gao, Qing, Ou, Zhou, Jiang, Teng, Tian, You-Yong, Zhou, Jun-Shan, Wu, Liang, Shi, Jian-Quan, Zhang, Ying-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421830/ https://www.ncbi.nlm.nih.gov/pubmed/28445961 http://dx.doi.org/10.18632/oncotarget.15732 |
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